Inter – Lazio Rome Tip, Prediction & Odds Serie A 09.11.2025

Home » Inter – Lazio Rome Tip, Prediction & Odds Serie A 09.11.2025

Inter Milan welcomes Lazio Rome to the Giuseppe Meazza on Sunday evening with an impressive record of five consecutive unbeaten head-to-head matches, crowned by a spectacular 6-0 away win in December 2024. The Nerazzurri sit in second place in Serie A with 21 points, just one point behind Napoli and level on points with AC Milan, while Lazio arrive in eighth place with 15 points and significant personnel concerns. Cristian Chivu’s team is excelling internationally with four wins from four Champions League games, most recently a 2-1 victory over Kairat, while the visitors are struggling with the absences of Niccolò Rovella, Abdoul Dele-Bashiru, and Jonathan Castellanos, despite their recent 2-0 home win over Cagliari. Inter are without Henrikh Mkhitaryan, Matteo Darmian, and Exequiel Palacios, forcing both coaches to make tactical adjustments.

  • Venue: Stadio Giuseppe Meazza, Milan
  • Date and time: 09.11.2025, 8:45 p.m.
  • Competition: Serie A (matchday 11)

Inter are clear favorites going into this match, which is reflected in the home win odds of around 1.40. The Nerazzurri have scored in all ten league games this season, netting 24 goals, while Marcus Thuram’s return further strengthens their attacking options. Lazio are traveling with seven regulars missing, which significantly affects their defensive stability.

There are three main bets to consider: A home win is based on Inter’s superior form and Lazio’s personnel problems. Over 2.5 goals looks promising, as Inter have scored at least two goals in each of their last five games and Chivu is increasingly relying on set pieces, which have already resulted in seven goals.

The market odds of around 8.5 for a Lazio win reflect the low expectations for the visitors. Nevertheless, surprises are always possible in soccer, especially due to unforeseen events such as early goals or red cards. A combination of a home win and over 2.5 goals offers a balanced risk-reward ratio, while more conservative bettors might focus on over 2.5 goals.

Inter form & record check

Inter Milan are in impressive form with four wins from their last five games, with only the 3-1 defeat in Napoli clouding the record. Their offensive power is particularly impressive: the team has scored in all of the games considered, consistently scoring at least three goals. Their strength in the second half is striking, with regular additional goals scored, which speaks for good fitness and effective tactical adjustments.

Internationally, they are doing even better than domestically: four wins from four Champions League games without conceding a goal until the most recent match underline their European class. Set pieces are becoming a particular weapon, with seven goals already scored from dead balls, demonstrating the successful work of set piece coach Angelo Palombo.

Defensively, there are occasional weaknesses, as evidenced by the three goals conceded in Naples and the goal conceded against Kairat. Nevertheless, the league goal difference remains strong at +12. The absences of Mkhitaryan, Darmian, and Palacios limit Chivu’s rotation options, but Barella is available again after serving his yellow card suspension against Kairat. Marcus Thuram’s comeback after a long break strengthens the offense at just the right time and significantly expands the tactical options for the coming weeks.

Inter are expected to line up in their tried-and-tested 3-5-2 formation. With Henrikh Mkhitaryan out injured, Nicolò Barella is likely to move into central midfield, flanked by Davide Frattesi and Piotr Zieliński in the half-positions. The back three of Alessandro Bastoni, Micky Bisseck, and Stefan de Vrij are all available, while Federico Dimarco and Denzel Dumfries will occupy the wide positions. Lautaro Martínez and Marcus Thuram are set to lead the line, with Thuram’s return after more than a month out through injury providing important momentum to the attack. Chivu has recently shown tactical flexibility with experiments such as a 3-4-1-2 formation with Frattesi as playmaker, underlining his willingness to vary his approach.

Lazio Rome Form & Record Check

Lazio have been solid defensively, with no defeats in their last five competitive games, 80% of which have ended with less than 2.5 goals. Three goalless draws and narrow wins against Juventus (1-0) and Cagliari (2-0) paint a picture of a team that prioritizes stability over spectacle.

The offense, on the other hand, is a cause for concern: with only 13 goals scored this season, the team is falling far short of expectations. Although Zaccagni and Isaksen have made an impact on occasion, overall the team lacks punch and efficiency in front of goal, which is particularly evident in low-scoring first halves.

The personnel situation is exacerbating the problems considerably. Castellanos and Dele-Bashiru are out with muscle injuries, Rovella is missing in midfield and Tavares in defense. Romagnoli left the game against Cagliari early at halftime, and his participation in Milan remains questionable. These absences are forcing Maurizio Sarri to make significant adjustments to his lineup. With 15 points in eighth place, level on points with Udinese and only two points behind Como in seventh, European places remain within reach, but the many draws and poor goal ratio are hindering higher ambitions.

Lazio are expected to line up in a 4-3-3 formation despite the tense personnel situation. Provedel will be in goal, with Lazzari, Gila, Patric, and Marusic likely to form the back four in front of him, with Nuno Tavares missing through injury. In midfield, Guendouzi and Cataldi will have to cope without the injured Nicolò Rovella, whose absence due to pubic bone inflammation will affect ball circulation. Blerim Basic is likely to take over Rovella’s position. Isaksen, Zaccagni, and Dia are expected to form the offense, while the possible transfer uncertainty surrounding Taty Castellanos creates additional pressure. On the bench, Pedro, Noslin, and Vecino are useful alternatives that Sarri can use for tactical adjustments or to freshen things up.

Inter – Lazio Rome Head-to-head comparison & statistics

The recent record clearly favors Inter: in the last five meetings, the Nerazzurri have remained unbeaten, celebrating three wins and two draws. Lazio have been waiting in vain for a win against the Milanese since January 2024. Particularly noteworthy is Inter’s dominance in the second half, which they have won in four consecutive encounters.

The 6-0 away win in December 2024 marks the high point of this series, followed by the 2-0 victory in the Coppa Italia quarter-finals in February. The last league duel at the Giuseppe Meazza ended 2-2 in May, with Pedro equalizing late on from the penalty spot, the only one of the five games in which both teams scored. Lazio conceded at least one goal in all five games and failed to score in three of them.

The first halves were mostly low-scoring, with less than two goals scored at the break in four of the five games. However, there were always at least two goals over the entire duration of the game, with Inter scoring in every match and Lazio only in the two draws.

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