Genoa – Lazio Rome Tip, Prediction & Odds Serie A 09/29/2025

Home » Genoa – Lazio Rome Tip, Prediction & Odds Serie A 09/29/2025

Four defeats in their last five league games have seen Lazio Rome slip to 13th in the table, while Genoa are three places lower with just two points from four games. On Monday evening, the Stadio Luigi Ferraris will host a crisis summit between two teams in desperate need of points. Adding to the drama: the dramatic Roma derby six days ago ended in chaos for the visitors when Belahyane and Guendouzi were sent off within two minutes of each other after Belahyane had equalized in the 85th minute. Genoa, on the other hand, recently gained some confidence with a 3-1 cup win against Empoli, with striker Colombo proving his quality. Historical dominance clearly favors Lazio, who have won four of the last five head-to-head matches, including a confident 2-0 win in April this year. The betting market rates this match as completely even, which seems understandable given the personnel problems of both teams: While Patrick Vieira only has to do without Jean Onana, Maurizio Sarri is missing four key players in Rovella, Gigot, Dele-Bashiru and the injured Lazzari.

  • Venue: Stadio Luigi Ferraris, Genoa
  • Date and time: 09/29/2025, 8:45 p.m.
  • Competition: Serie A (Matchday 5)

Genoa form & record check

Genoa is currently struggling for consistency in Serie A and is in 16th place in the table with only two points. The Rossoblu have had a mixed season so far, with Patrick Vieira’s influence not yet fully established. Only one point separates them from Verona in 15th place, while Fiorentina lurks in 17th place with the same number of points. Their recent league record paints a typical picture for teams at the bottom of the table: after a goalless start to the season against Lecce and a 0-1 home defeat to Juventus, they followed up with a 1-1 draw against Como and most recently a narrow 1-2 defeat to Bologna. Genoa’s weakness in the first half is striking, with hardly any goal threat developed in four of their five league games. The team has also conceded goals in four of its last five games, highlighting its defensive problems. Only in the cup game against Empoli did the offense show its better side. Onana, an important midfielder, will be out until the beginning of October, whose presence in the center could provide more stability.

Vieira is likely to field his team in the tried-and-tested 4-2-3-1 formation. Leali could start in goal, while the defense is likely to consist of Sabelli, Marcandalli, Vásquez, and Aarón Martín. Frendrup and Stanicu could form the double six in midfield. The attacking trio could consist of Carboni, Grønbæk, and Messias, with Colombo as the lone striker. Vieira will have to do without Onana, who is out until October due to injury, but he has enough alternatives at his disposal to be able to act flexibly.

Lazio Rome Form & Record Check

Lazio Rome is stuck in a worrying phase. Maurizio Sarri’s team has lost four of its last five league games, with only a 4-0 home win against Verona at the end of August breaking this negative streak. The bitter 0-1 defeat in the derby against AS Roma six days ago was the low point so far. Recent performances have revealed clear weaknesses in the team’s attacking play: in 80% of their last five games, Lazio scored less than 1.5 goals across both halves. This lack of goals explains their disappointing 13th place in the table. The Roma derby exemplified the current problems when, despite Belahyane’s late equalizer in the 85th minute, two red cards for Belahyane and Guendouzi followed within two minutes. This lack of discipline ultimately cost them an important point in the city derby and underlined the team’s mental instability. Statistics show that Lazio have not drawn a single game in their last five, indicating an unusual tendency toward extreme results. With only three points from four league games, the team is level on points with Sassuolo and only one point ahead of bottom-placed Fiorentina, which is far below expectations for the season.

Lazio are likely to line up in their usual 4-3-3 formation, which has become the standard under Sarri. Provedel will be in goal, while the back four could consist of Marusic, Gila, Romagnoli, and Tavares. The midfield will have to do without the injured Rovella, who is suffering from pubic bone inflammation. Guendouzi, Cataldi, and Vecino could form this important midfield trio. The absence of Dele-Bashiru due to his thigh injury forces Sarri to make adjustments in attack. The trio of Isaksen, Castellanos, and Zaccagni are expected to start up front, with Pedro available as an experienced alternative. Lazzari’s calf problems mean that Marusic is likely to play at right-back.

H2H Genoa – Lazio Rome Head-to-head comparison & statistics

The head-to-head record from the last five meetings speaks for itself: Lazio dominates with four wins, while Genoa has only triumphed once. That sole victory came away in Rome in August 2023 with a narrow 1-0 win. Since that surprise victory, however, nothing has gone right for Genoa against the Biancocelesti. The Rossoblu have suffered four defeats in a row, including two heavy home defeats and a 2-0 defeat in April 2025. The 3-0 defeat in Rome in October 2024 must have been particularly painful. The pattern of the encounters is striking: the games are usually uneventful in the first half, before the decision is made in the second half. In all five duels, there was no more than one goal at half-time. Lazio’s efficiency is particularly evident in defense, as the team from the capital has not conceded a goal after the break in four of its last five games, while Genoa has remained completely silent in the second half.

The tip for under 1.5 goals in the first half is based on recent performances: Both Genoa and Lazio have failed to score before the break in 80% of their league games so far, with four of Genoa’s five games this season featuring goalless first halves. The compact midfields of both coaches and Lazio’s personnel problems on the wings further reinforce this trend. The second tip against both teams scoring is backed up by Lazio’s current goal drought, as the Romans have failed to score in four of their last five games, while Genoa’s defense has only allowed Juventus to score more than one goal at home. The betting market rates this match as very even, with almost identical odds for all three outcomes, but the home win tip at 3.0 could well offer value. Genoa’s recent cup victory showcased Colombo’s qualities in the center of attack, and with four key Lazio players injured or carrying knocks, the visitors’ odds of 2.55 seem almost too low for a team that has lost four of its last five games.

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